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# The vast epithelial lining of the gut has its own branch of the immune system to protect the body from invasion.
In his Perspective, Shanahan describes the components of this system--the intestinal epithelial cells and intraepithelial lymphocytes--and a new local paracrine network among them, mediated by thyrotropin-releasing hormone and thyroid-stimulating hormone and reported in this issue on p.
(, Sun 27 Apr 2008, 3:25, archived)