Hmm.In a 6-week, double-blind, placebo-controlled, randomized study, 23 subjects with body-mass indices more than 25 kg/m 2 were assigned to 1 of 3 groups. Group A received a mixture containing C. aurantium 975 mg (6% synephrine alkaloid), St. John's wort 900 mg (3% hypericin), and caffeine 528 mg; group B received a maltodextrin placebo; and group C was a control without placebo.
(,
Sat 4 Oct 2008, 2:41,
archived)
Because of the potential for additive effects, synephrine use should be avoided in patients with hypertension, tachyarrhythmia, or narrow-angle glaucoma.Ephedrine and synephrine are banned by many sports agencies. A single dose of a commercially available synephrine product did not cause a false-positive response in an amphetamine assay.
(
gronkpan @vomitinglarry.bsky.social,
Sat 4 Oct 2008, 2:42,
archived)
