Not so much pranks
As a long-term investigation into the placebo effect that I've been conducting for approximately 5 years.

A good 90% of my mates, like myself, get their fun through the consumption of various chemicals. Things I have done include:

Giving out lines of coffee whitener/ baking soda, rolling 3-skinner cigs and passing them round, sorting my mate some Valium which were really paracetamol, same principle as previous but with ecstasy/ flu pills and the piéce de résistance, printing designs onto and then meticulously perforating a piece of A4 sketch paper so that it resembled acid.

The funny thing is, I have yet to receive any complaints, and on several occasions have been congratulated on my procurement of exceedingly fine substances.

I'm a cunt, yes, but there's nothing funnier than seeing your mate's sister "coked out of her mind" on baking soda, and your mate himself tripping the light fantastic with unsprayed blotter.
(hypnoticme is an anarcho-syndicalist commune, Wed 19 Dec 2007, 17:26, 5 replies)

As long as the substances are harmless
I'd say it's a prank well worth continuing!
( The Resident Loon Not a demographic. Do not measure., Wed 19 Dec 2007, 17:30, closed)

^ What he said
This summer we had a party at our place, with a bunch of friends around. As the evening drew on we moved from beer/wine to spirits, and some expressed an interest in our single malts. One friend suggested I replace his brother's wee dram of Highland Park (yum) with a measure of Teacher's (meh).

Most obligingly, the victim made a point of extolling on the merits of single malts versus 'inferior' blends, thereby making a bit of a twat of himself.

Tee hee.
( reallywittyname veraciously conspues lexiphanicism on, Wed 19 Dec 2007, 17:42, closed)

Had the reverse happen to me...
My first ever time trying to smoke weed....I was not impressed. Got a better buzz from a large glass of wine.
( chickenlady b3ta's very own Elizabeth Taylor, Wed 19 Dec 2007, 18:32, closed)

weed
never gives you the buzz when you smoke it for the first time... so I've been told, and turned out to be true in my case.
(mtp, Wed 19 Dec 2007, 23:13, closed)

Shulgin
Is a pioneering psychedelic chemist, discovering and testing on himself over 200 new and unusual trippy things... and once sent himself to sleep convinced that he'd been given a premed.. which was just sugar in the bottom of a glass...
(Countryslicker, Thu 20 Dec 2007, 12:22, closed)