You won't read this. And in response you'll say, "You're right, I won't!" Or you'll say, "Joke's on you, I DID read it, and it was crap." Or you'll pretend to be smart and say it doesn't make sense. After all, you watch Mythbusters.Replication factor C 4, 37kDa (in humans) is a gene activated in the polymerase reaction phase of eukaryotic DNA replication which controls the partial synthesis of DNA passed to the G1/S checkpoint, allowing cell replication to occur. Segments bearing cyclins that do not pass the checkpoint are paired with a particular sequence of stop codons, unique to each gene, and the formation of relevant stop codons is linked to ATPase activity via an electron-dependent protein reaction. Disruption of the electron supply causes an excess of free radicals, though previously the mechanism of this disruption was not known. More than 99% of the carbon in the ATP synthase suspension membrane consists of carbon-12 and the common isotope carbon-13. An infinitesimal fraction (one in a trillion) exists as carbon-14, a radioactive ionizing isotope. When an H+ ion passes through ATP synthase it enters DNA polymerase production, lining the edge of DNA strands ready for pairing. When a positively charged stop codon is encountered, the H+ ion is repelled and synthesis ceases. The trouble comes when a carbon-14 atom randomly undergoes beta decay and releases an electron 'downstream' from ATP synthase. If the electron encounters the H+ ion, it is neutralized, bonding cannot occur, and RFC4-37kDa never receives the instruction to stop. Cytokinesis occurs without restraint and a tumor forms.
Given that carbon-14 exists within all sources of carbon, and thus cannot be avoided, it stands that exposure to carbon in general is proportionate to risk for cancer. Smoke, soot, acids, nitrogen-carbon compounds (in many industrial pollutants) are all known carcinogens. Neutron irradiation of nitrogen in the upper atmosphere leads to the formation of carbon-14, linking it to the presence of ultraviolet light.
I have found that stop codons in RFC4-37kDa can be triggered by rapid ionization of cells by silver ions prior to polymerase production. Unrestrained cytokinesis ceased in 64% of mottled duskywing moths I tested, while healthy cytokinesis continued in 98% of those. I cured cancer in moths.
(
Digeridude Lord Wellington's Beef Trapeze, Tue 14 Oct 2008, 18:11,
archived)
I read the last sentence. Nice one(
SugarSpunSister Yeah, whatever, Tue 14 Oct 2008, 18:13,
archived)
me too,fair play, doesn't mean squat to me though, i hate moths.
(
mostly harmless John Leslie raped me on, Tue 14 Oct 2008, 18:14,
archived)
And it only cost me half my life savings!Hopefully I'll get cancer so it won't be in vain.
(
Digeridude Lord Wellington's Beef Trapeze, Tue 14 Oct 2008, 18:14,
archived)
what happened to the other 2%those that didn't have healthy cytokinesis?
(, Tue 14 Oct 2008, 18:21, archived)
They developed super powers.(
Digeridude Lord Wellington's Beef Trapeze, Tue 14 Oct 2008, 18:23,
archived)
What were you making an FT17 for?www.digeridude.com/images/tankpart_mesh.jpg
(
Bobson I who milks the milkmen?, Tue 14 Oct 2008, 18:21,
archived)
I'm a game developer for a living.(
Digeridude Lord Wellington's Beef Trapeze, Tue 14 Oct 2008, 18:24,
archived)
Nintendo DS games, but nothing famous. Kids games. Worked on Transformers.The tank was just for fun.
(
Digeridude Lord Wellington's Beef Trapeze, Tue 14 Oct 2008, 18:26,
archived)
so you cure cancer in your spare time?(
minimum fuss - an all time favourite, Tue 14 Oct 2008, 18:27,
archived)
he said it on the internet from his bedroom, it MUST be true!(
moohalaa, Tue 14 Oct 2008, 18:28,
archived)
Well, there's certainly enough evidence for The Sun to publish it(
minimum fuss - an all time favourite, Tue 14 Oct 2008, 18:30,
archived)
If you were able to remove all the empty space in and around atoms in the human bodyyou would be able to fit the whole of the human race in the space the size of a sugar cube
(
Hankster, Tue 14 Oct 2008, 18:22,
archived)
Show your workingHow big do you reckon atoms are, then? I reckon it'd be a volume much, much smaller than that
(
Cap'n Tallbeard, Tue 14 Oct 2008, 18:24,
archived)
I know,stunning isn't it.
I haven't studied nuclear physics for three years to be made a fool of you know
I also nearly know ALL my nine times table
(
Hankster, Tue 14 Oct 2008, 18:28,
archived)
WRONG.www.b3ta.com/talk/1512454
(
The Mock TurtIe ™ --- Thinks you are a cunt, on, Tue 14 Oct 2008, 18:29,
archived)
He's much smarter than us all.The man can bend spacetime!
With his bare hands!
(
moohalaa, Tue 14 Oct 2008, 18:31,
archived)
I'm usingthis right now to go back in time and prove you wrong.
(
Druid, Tue 14 Oct 2008, 18:32,
archived)
in only 24h rotations?4 Corner TIME, CUBES EARTH.
If a God existed, he would be EVIL
to DENY 4 Opposite Corner Days.
Greenwich Mean Time divides the
Earth into opposite Days, voiding
and contradicting the 1Day 1God
Bible?
(
glued eel /questions/questionsyoudliketoask/post1648081, Tue 14 Oct 2008, 18:27,
archived)
Die lonely, you definition of pointlessness.(
Dr. Shambolic je suis charlie, Tue 14 Oct 2008, 18:13,
archived)
No silver ions for you, Sonny Jim.(
Digeridude Lord Wellington's Beef Trapeze, Tue 14 Oct 2008, 18:15,
archived)
Fine. See if I care.I'm just going to keep bashing myself against this bright light until my wings fall off.
(
Dr. Shambolic je suis charlie, Tue 14 Oct 2008, 18:16,
archived)
In moths, yeah. It'll be much harder in humans, but I've still got to test small mammals.Problem is, I love fluffy aminals and was sad when some of the moths died. =(
(
Digeridude Lord Wellington's Beef Trapeze, Tue 14 Oct 2008, 18:16,
archived)
I saw a moth die last nightIt flew into the light, then fell on me, then I flicked it off me, killing it in the process.
(
minimum fuss - an all time favourite, Tue 14 Oct 2008, 18:19,
archived)
I understood most of thatwell done. let's hope it's eventually repeatable in humans. :)
(
Fluzzy namby-pamby pudding and pie, Tue 14 Oct 2008, 18:14,
archived)
Let us not forget that this is the man who claims to be able to travel in timeand is actually from the future.
(
Wicca'd Witch needs ideas for a new sig on..., Tue 14 Oct 2008, 18:17,
archived)
Yup.He used to post on here late at night and tell us about his time machine.
(
Wicca'd Witch needs ideas for a new sig on..., Tue 14 Oct 2008, 18:21,
archived)
True, but if a man walked up to you in the street and told you he was the second coming of Jesus, would you believe him?/don't know where I'm going with this
*whistles*
oooh, a butterfly!
(
minimum fuss - an all time favourite, Tue 14 Oct 2008, 18:23,
archived)
I'd ask him why he thought that.(
Wicca'd Witch needs ideas for a new sig on..., Tue 14 Oct 2008, 18:25,
archived)
and ask after his toaster? ;)(
Fluzzy namby-pamby pudding and pie, Tue 14 Oct 2008, 18:26,
archived)
It's such a simple techniquebut the concept has really made complaint handling a doddle :)
(
Wicca'd Witch needs ideas for a new sig on..., Tue 14 Oct 2008, 18:29,
archived)
I don't know about you, but the first thing I'd do if I made a time machineor cured cancer is tell the internet.
(
Druid, Tue 14 Oct 2008, 18:23,
archived)
Does he have a white labcoat & frizzy hair?"I'll be able to take over the WOOOORLLLDD!!!"
THUD THUD *muffled shouts*
"SHUT UP GRANDMA!"
(
moohalaa, Tue 14 Oct 2008, 18:24,
archived)
Some people can't tell the difference between fact and fiction.Hint: I'm not one of them.
(
Digeridude Lord Wellington's Beef Trapeze, Tue 14 Oct 2008, 18:27,
archived)
Oh I can. I can also spot a talented author when I see them.Hint: You're not one of them.
(
Wicca'd Witch needs ideas for a new sig on..., Tue 14 Oct 2008, 18:33,
archived)
That's correct.I've never written a book.
(
Digeridude Lord Wellington's Beef Trapeze, Tue 14 Oct 2008, 18:36,
archived)
And doesn't believe in the basic rules of mathematics.So in many ways, it makes perfect sense for him to do biology.
(
The Mock TurtIe ™ --- Thinks you are a cunt, on, Tue 14 Oct 2008, 18:20,
archived)
I am not from the bloody future.(
Digeridude Lord Wellington's Beef Trapeze, Tue 14 Oct 2008, 18:21,
archived)
Sorry. My mistake.You visit the future.
(
Wicca'd Witch needs ideas for a new sig on..., Tue 14 Oct 2008, 18:22,
archived)
and something somethign 1.21 jiggawatts and KAPOW! I've ended Third World poverty or some such(
moohalaa, Tue 14 Oct 2008, 18:15,
archived)
For fucks sakeI couldn't give 2 shits about moths, my grandad died of cancer, and my aunt now have it. Stop pissing about with moths, work on humans.
(
magnum, Tue 14 Oct 2008, 18:15,
archived)
Alright, care to be a guinea pig for my massive, untested death machine?(
Digeridude Lord Wellington's Beef Trapeze, Tue 14 Oct 2008, 18:18,
archived)
Can she get to New York?Oh shit, I'm moving to Chicago soon. How am I gonna move this thing?
(
Digeridude Lord Wellington's Beef Trapeze, Tue 14 Oct 2008, 18:42,
archived)
Not bad....
For a humannnnnnn
(
whenanimalsattackhumans clad in global hypercolour, Tue 14 Oct 2008, 18:18,
archived)
Maybe he can use your aunt as a guinea pig(
OneSullenBrit *air sandwiches*, Tue 14 Oct 2008, 18:19,
archived)
Shouldn't you be telling New Scientist or Cancer Monthlyor anyone other than b3ta really?
(
minimum fuss - an all time favourite, Tue 14 Oct 2008, 18:18,
archived)
I'm actually telling New Scientist now.It's now officially my idea.
(
mike woz ere 7442200 & 7696970 getter, Tue 14 Oct 2008, 18:19,
archived)
As interested in a cure for cancer as I am, in the short term, I'd be much happier if someone would fix the full tilt poker servers/can't connect
(
minimum fuss - an all time favourite, Tue 14 Oct 2008, 18:21,
archived)
Already in contact with someone.But there's a stigma associated with saying "cure for cancer." People immediately dismiss it, so I'll need to win the trust of institutions by offering a real treatment for free one day. That'll be many years, though.
(
Digeridude Lord Wellington's Beef Trapeze, Tue 14 Oct 2008, 18:20,
archived)
plus, at mostyou might have partially blocked one, fairly obscure, route of cellular mutagenesis. People tend to be more impressed when you can block the major routes.
(
the mighty badger Aphrodite, on a bar stool, by your side, Tue 14 Oct 2008, 18:31,
archived)
CANCER MOTHLY(
whenanimalsattackhumans clad in global hypercolour, Tue 14 Oct 2008, 18:24,
archived)
They only let you sign up for monthly recurring subscriptions.=D
(
Digeridude Lord Wellington's Beef Trapeze, Tue 14 Oct 2008, 18:28,
archived)
this month's edition delayedas someone switched on the light in the office next door
(, Tue 14 Oct 2008, 18:31, archived)
it's an interesting, but almost certainly fairly meaningless set of data.and the theory behind it is wrong. I doubt we'll be seeing it in Nature in the near future. Mind, some of the shit that gets published these days, who knows?
(
the mighty badger Aphrodite, on a bar stool, by your side, Tue 14 Oct 2008, 18:28,
archived)
I read it all. Good stuff.If only I were a cancerous moth.
(
Cap'n Tallbeard, Tue 14 Oct 2008, 18:18,
archived)
Nice use of thousands of pounds worth of resources, there./Jealous that you made something of your life.
(
The Gentleman Bastard waxing lyrical. ©, Tue 14 Oct 2008, 18:19,
archived)
So, in summary:lOLolOLololOLlOLololOLololOLolOLlOLololOLolOLLolOLolOLOLolololollOLolOLollolololOLOLOLolOLlOLolololOLolOLOLOLOLBZZzzZZZZzBzzzZZzZZZLollOLOLOLOLOLolOLOLOLOLLolololOLOLolOLOLOLollOLOLOLOLolBzzZzzzzzzLOLOLololOLOLolOL
(
The Mock TurtIe ™ --- Thinks you are a cunt, on, Tue 14 Oct 2008, 18:20,
archived)
congratulations on stringing several related words together(
glued eel /questions/questionsyoudliketoask/post1648081, Tue 14 Oct 2008, 18:23,
archived)
*ahem*"Given that carbon-14 exists within all sources of carbon, and thus cannot be avoided, it stands that exposure to carbon in general is proportionate to risk for cancer. Smoke, soot, acids, nitrogen-carbon compounds (in many industrial pollutants) are all known carcinogens. Neutron irradiation of nitrogen in the upper atmosphere leads to the formation of carbon-14, linking it to the presence of ultraviolet light."
No. No. NO.
You are talking about carbon atoms in the make-up of cells. "exposure to carbon" does not result in "carbon atoms being miraculously incorporated into basic cellular structure"
that generally comes from metabolism of carbon-based food sources. So if you've worked out a way of metabolising soot, you've done a fuck sight more than cure cancer. Otherwise, I suggest a serious re-appraisal of your theory. Interesting work on the moths, mind.
(
the mighty badger Aphrodite, on a bar stool, by your side, Tue 14 Oct 2008, 18:26,
archived)
This doesn't require braininessit requires a good 'Fuck off you cock end'
Hello you
(
Blue Star was working part time at the 5 and Dime, Tue 14 Oct 2008, 18:30,
archived)
Stop being cleverThis is the internet, only psuedoscience is allowed.
(
Wicca'd Witch needs ideas for a new sig on..., Tue 14 Oct 2008, 18:31,
archived)
fuck, yeah, I forgot that.I'll go back to wanking and "tits or GTFO", shall I?
(
the mighty badger Aphrodite, on a bar stool, by your side, Tue 14 Oct 2008, 18:36,
archived)
*raises eyebrow**chuckles*
(
Wicca'd Witch needs ideas for a new sig on..., Tue 14 Oct 2008, 18:39,
archived)
And even if they were metabolised,the very low natural abundance of 14C would make cell damage due to radioactive emissions an extreme improbability.
(
The Mock TurtIe ™ --- Thinks you are a cunt, on, Tue 14 Oct 2008, 18:33,
archived)
STOP IT STOP IT STOP IT.(
Wicca'd Witch needs ideas for a new sig on..., Tue 14 Oct 2008, 18:35,
archived)
If you have a question, you can ask it in a civilized manner instead of giddily poking at loopholes in my logic like a schoolgirl.I mean exposure in the environmental sense, not simply exposure to the skin. Pollutants make their way into water supplies, smoke settles on surfaces and is inhaled as dust, then swallowed.
It may be insignificant, but C14 is an extremely potent carcinogen. I'm still amazed we don't ALL get cancer.
(
Digeridude Lord Wellington's Beef Trapeze, Tue 14 Oct 2008, 18:35,
archived)
*gets popcorn**settles down on sofa*
(
Wicca'd Witch needs ideas for a new sig on..., Tue 14 Oct 2008, 18:41,
archived)
You know, I used to like you on the main board and in QOTW.Why the attitude towards a complete stranger?
(
Digeridude Lord Wellington's Beef Trapeze, Tue 14 Oct 2008, 18:44,
archived)
I happen to know what Mighty Badger does for a living.(
Wicca'd Witch needs ideas for a new sig on..., Tue 14 Oct 2008, 18:45,
archived)
This isn't an argument between him and me. I know what he does as well, but your point is invalid.Stop attacking a stranger. I'd rather not talk to you.
(
Digeridude Lord Wellington's Beef Trapeze, Tue 14 Oct 2008, 18:55,
archived)
well then don't claim you've cured canceryou pillock. You haven't. Even if your data is right, there's tiny chance you've blocked one route of unrestricted replication. What about acclerated cell growth? defective apoptosis routes? site-spectific mutagenesis? external mutagenesis agents? You're not even scratching the surface.
You should also know, I would have thought, that insect data is more or less meaningless in mammals anyway. Different cellular replication pathways.
And in any case, method of exposure is irrelevant. repeat after me. WE. CAN'T. METABOLISE. SOOT. OR. SMOKE. So, tell me again how you think C14 is planning to incorporate itself into your basic celluar structure to do this damage?
(
the mighty badger Aphrodite, on a bar stool, by your side, Tue 14 Oct 2008, 18:43,
archived)
1. 37kDa is present and has identical function in humans and many insects.
2. I didn't say I cured all cancer for everyone. I cured 64% of a sample of MOTHS, so obviously there are countless routes to still take.
3. There is carbon in your body. It doesn't have to be incorporated into any cellular structure. It merely has to be in some proximity of ATP synthase.
4. The human digestive tract is imperfect and carbon can be metabolized when bonded to hyrdrogen.
5. Simple chemical reactions can disassociate carbon from hydrogen.
6. Stop calling names, it just makes you sound like a child.
(
Digeridude Lord Wellington's Beef Trapeze, Tue 14 Oct 2008, 18:52,
archived)
If you think calling you a pillock is badyou're a wee bit sensitive.
1) no it doesn't.
2) semantics. you didn't cure it. you stopped some unrestriceted cell replication
3) exactly how far do you think an electron from C14 decay will travel? it's nanometres. if it's not in the cellular structure it won't get near ATP synthase.
4) no it can't. it needs a C-O bond for metabolism
5) eh? what does that matter?
6) I'm more than willing to hold a serious conversation with someone who doesn't usually post fabricated bullshit on here. My apologies for judging you on the basis of your previous posts. If you want a serious discussion, Gaz me.
i'm off to the pub. have to at least pretend to have an offline social life..
(
the mighty badger Aphrodite, on a bar stool, by your side, Tue 14 Oct 2008, 19:02,
archived)
All you've done is contradict every claim without offering an explanation.You've clearly developed a sour disposition in response to my apparent knowledge of biology. If it makes you feel better, I'll admit my biology is weak - I'm aware of that.
I'm an engineer, and this was something I thought was interesting.
Edit: Why is everyone I talk to a drunk?
(
Digeridude Lord Wellington's Beef Trapeze, Tue 14 Oct 2008, 19:08,
archived)
I'm an engineer toowhy would it make me feel better? this isn't a game of one-upmanship. Any progress in this area is fucking important. But you flippantly put forward something as progress which isn't. I don't understand what explanation you want? you've stated facts that are wrong. There isn't any explanation. Sorry if that offends. I don't have a sour disposition. I've spent 13 years of my life working with cancers and various other diseases. I take it fairly seriously.
(
the mighty badger Aphrodite, on a bar stool, by your side, Tue 14 Oct 2008, 19:15,
archived)
All that leans towards the fact that you're frustrated with your work.Please point to the sentence where I stated any of the following:
"I cured all cancer for everyone!"
"This is important and no one has ever done it!"
"I know more than badger!"
Edit: And I'm not that sort of engineer. I program games, make robots, and generally tool around with shit. Hell, I'm an artist by trade.
(
Digeridude Lord Wellington's Beef Trapeze, Tue 14 Oct 2008, 19:27,
archived)
you fucking bastard, i hate moths.(
Sir Sand GOBLIN ^popular page dis, Tue 14 Oct 2008, 18:30,
archived)