I disable them.
Also, I hate pricks who phone you the second they've hit send.

No, of course I haven't read the email you sent 0.4 seconds ago.

I've also recently created a rule that automatically bins messages I'm CC'd in. They're nearly always irrelevant to my interests.
( Slippery Mick ‏, Fri 28 Jun 2013, 13:00, 2 replies, latest was 12 years ago)

My firm is shut over the weekend.
Every Monday, without fail, by 9:15am we get a call from some spastic who has also
a) sent an email over the weekend and
b) left an answerphone message

I detest my customers, they are utter mongols.
( Monty Boyce, My cheese game is strong, Fri 28 Jun 2013, 13:09, Reply)

Also see arsey cunts that think by CC'ing your boss into email
it's going to make things happen any faster
( hartley hare Just some prick who thinks it doesn't apply to him, Fri 28 Jun 2013, 13:21, Reply)

To be fair to my boss that usually elicits an
"Who the fuck is this prick? Fuck off" from him. My boss has his upsides.
( Kroney, Fri 28 Jun 2013, 13:26, Reply)

Good for him

( hartley hare Just some prick who thinks it doesn't apply to him, Fri 28 Jun 2013, 13:28, Reply)

Yes!
I love smacking reply all and showing them up in front of everyone they've cc'd in.
( Slippery Mick ‏, Fri 28 Jun 2013, 14:38, Reply)