Not really
They're all near immortal (one arguably is)
( Agnostic Antichrist Baltimora, Wed 29 Sep 2010, 9:33, 2 replies, latest was 15 years ago)

I want Sephiroth to win this a lot.

( SteveFrench Cardio is for homo's. do you even lift bro?, Wed 29 Sep 2010, 10:02, Reply)

Granted
But Superman is virtually invulnerable too. I would be quite interested to see how he'd deal with a seriously pissed-off Tetsuo though
(Darth Foxtrot A one-man army dedicated to making fetch happen, Wed 29 Sep 2010, 10:04, Reply)

Seen as Tetsuo is psychic, reckon he'd just make Superman start punching himself in the face?

( Agnostic Antichrist Baltimora, Wed 29 Sep 2010, 10:14, Reply)

This was always my problem with Superman
It seemed to be entirely up to the whim of the writers as to what did and didn't affect Superman. Good idea though, surely at least he could hurt himself.

That said, Superman did eventually get the shit kicked out of him by Doomsday so maybe he's only invulnerable to earthly stuff like bullets an' that. In which case Sephiroth's fuck-off bastard sword might be reasonably effective
(Darth Foxtrot A one-man army dedicated to making fetch happen, Wed 29 Sep 2010, 10:20, Reply)