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# Poor Vagabond cannot drink this weekend as he is on antibiotics.
Other than suicide, what do the esteemed members of the board suggest I do with myself?
(I helped save b3ta! Je suis un vagabond is an unfunny, up your own arse middle class knob, Fri 27 Mar 2009, 16:12, archived)
# Frantic self abuse
While hidden in a wardrobe
(I helped save b3ta! The magic of chutney Shakes it like an Instagram filter!, Fri 27 Mar 2009, 16:13, archived)
# Play?
(I helped save b3ta! Fresh Water Mole loves his baby boy more and more every day, Fri 27 Mar 2009, 16:14, archived)
#
(I helped save b3ta! ..wil, Fri 27 Mar 2009, 16:20, archived)
# awwww
I have a collie looking at me with the exact same expression right now! (including tennis ball in mouth for bonus points)

Walk time I guess
(I helped save b3ta! The magic of chutney Shakes it like an Instagram filter!, Fri 27 Mar 2009, 16:22, archived)
# perhaps he just wants to be your gimp?
(I helped save b3ta! Griffin Saver Something, something, 2006, something., Fri 27 Mar 2009, 16:23, archived)
# ha ha ha no
It's the prelude to the usual game of: me throwing ball, her running after it picking it up then NOT bringing it back
(I helped save b3ta! The magic of chutney Shakes it like an Instagram filter!, Fri 27 Mar 2009, 16:24, archived)
# got the extra collars on eh?
(I helped save b3ta! Griffin Saver Something, something, 2006, something., Fri 27 Mar 2009, 16:26, archived)
# Smoke weed
(I helped save b3ta! mofaha ┐( ˘_˘)┌ ʅ(́◡◝)ʃ, Fri 27 Mar 2009, 16:19, archived)
# it's only certain antibiotics that react badly with alcohol
experiment and see if yours is one of them.
(I helped save b3ta! arrangedletters, Fri 27 Mar 2009, 16:21, archived)
# They don't react badly in the slightest.
The only reason for not taking alcohol whilst on antibiotics is that the alcohol competes with the drug for the enzymes in the liver needed to metabolise it. The alcohol wins and this means that the antibiotic ends up going through the system without metabolising and ultimately being as much use as smarties.
No point taking antibiotics with drink because the drugs don't work.
Any other idea about being messed up whilst on both is urban myth.
(I helped save b3ta! Pasanonic 's been known to cause insanity in laboratory mice, Fri 27 Mar 2009, 16:45, archived)
# Yes and no
en.wikipedia.org/wiki/Antibiotics#Alcohol
Well, no, really.
(_Felix 's school of dance and occult sciences, Fri 27 Mar 2009, 16:58, archived)
# My doctor drinks in my
pub and I remember having this conversation over booze.
I'm happy to take my hazy recollection of his word over Wiki anyday. ( I'd take any fact I heard in the pub before I'll take Wiki at face value ).
(I helped save b3ta! Pasanonic 's been known to cause insanity in laboratory mice, Fri 27 Mar 2009, 17:01, archived)
# I know you hate wikipedia
So here are the websites which wikipedia cites:
www.nhs.uk/chq/pages/871.aspx?CategoryID=73&SubCategoryID=103&r=1&rtitle=http%3a%2f%2fwww.nhs.uk%2fchq+-+871%3fCategoryID%3d73%26SubCategoryID%3d103
www.mayoclinic.com/health/antibiotics-and-alcohol/AN01802
You're right in as far as it's probably alright to drink on antibiotics, but wrong in that if they're rarer kinds, you'll end up puking. You're half-right that alcohol might make the antibiotics stop working, but again, it depends what they are, and usually it won't. (And I don't get the metabolising part - I mean, sure, you don't metabolise the antibiotics, but that just means they don't get broken down, so they'd keep working for longer, wouldn't they?)
(_Felix 's school of dance and occult sciences, Fri 27 Mar 2009, 17:06, archived)
# I'm not a chemist so I'm out of my depth here
But I understand that the antibiotics make their way through your system at a set rate and the more of it going into your faeces the less effective it is. ( I think )

And I'm not saying it's ok to drink and take them. What would be the point? I'm just saying that there are many myths about it and only 5 or so antibiotics known to doctors to cause any kind of side-effect.
(I helped save b3ta! Pasanonic 's been known to cause insanity in laboratory mice, Fri 27 Mar 2009, 17:11, archived)
# I guess the thing is
if you can't metabolise the antibiotic, it's like taking a bigger dose, and that might not be pleasant.
(_Felix 's school of dance and occult sciences, Fri 27 Mar 2009, 17:18, archived)
# *recovers sense of humour*
"My doctor drinks in my pub and I remember having this conversation over booze."
Ha ha, he must have been on the metronidazole first. :-S
(I helped save b3ta! Bee Nice |-|, Fri 27 Mar 2009, 17:43, archived)
# No, that's wrong.
(Or at least dangerously incomplete).
See:
www.nelm.nhs.uk/en/NeLM-Area/Evidence/Medicines-Q--A/Which-oral-antibiotics-interact-with-alcohol/
(It's a .doc, I'm afraid. Try Google's HTML rendering of it).
(I helped save b3ta! Bee Nice |-|, Fri 27 Mar 2009, 16:59, archived)
# Hmmm, I didn't know that (to my shame :)
But it seems like one or more of:

a) Alcohol competes for detoxifying enzymes, so leaving more of the antibiotic around for more intense side-effects

b) Heavy drinkers produce more detoxifying enzymes, so the drug is less effective (is broken down faster)

c) Alcohol can increase the sedative effect of some drugs, but also the effects of alcohol can be increased by the same sort of competing for binding sites.

Phew! (from : www.steadyhealth.com/articles/Antibiotics___Alcohol__The_truth_and_myths_a144_f0.html)
(I helped save b3ta! The Alchemist king of the needlessly complicated, Fri 27 Mar 2009, 17:05, archived)
# I'm happy to concede that
there are a handful of antibiotics that can react with alcohol ( high blood pressure being the main effect I think ) but the absolute reason for not drinking is simply because it reduces their effects and you may as well not be taking them.
(I helped save b3ta! Pasanonic 's been known to cause insanity in laboratory mice, Fri 27 Mar 2009, 17:08, archived)
# From the NHS NeLM:
"1. Metronidazole (AVOID ALL ALCOHOL)

Metronidazole can inhibit the metabolism of alcohol, so that metabolites build up in the body. These metabolites cause an unpleasant reaction characterised by symptoms such as flushing, nausea, vomiting, headache, hypotension, and palpitations (1-5). Not everyone is affected, but it is a common enough reaction for all people on metronidazole to be advised to avoid alcohol."

Metronidazole is certainly a commonly prescribed antibiotic.

The same document does say "Members of the public commonly believe that all antibiotics interact with alcohol. This is not true." They should have spelled "all" "ALL".
(I helped save b3ta! Bee Nice |-|, Fri 27 Mar 2009, 17:12, archived)
# You are throwing words at me as though I suggested
that people should drink and take antibiotics. Far from it. I'm just disputing the misconceptions behind why you are told not to.
(I helped save b3ta! Pasanonic 's been known to cause insanity in laboratory mice, Fri 27 Mar 2009, 17:15, archived)
# It's nothing personal.
But the words "They don't react badly in the slightest" are wrong*, and might make someone ill if they acted on them.

(I agree with you that there are a lot of myths floating around on both sides).

(*: assuming we trust the NHS National electronic Library for Medicines (NeLM) as a competent authority. The Hedgehog From Hell, where are you? :-)
(I helped save b3ta! Bee Nice |-|, Fri 27 Mar 2009, 17:20, archived)
# there's some
a very very small minority.. that actually react with the alcohol. My weekend plan for Mr. V was to see if it was one of them :)
(I helped save b3ta! arrangedletters, Fri 27 Mar 2009, 17:09, archived)
# I hear autoasphyxiation is good
(I helped save b3ta! Griffin Saver Something, something, 2006, something., Fri 27 Mar 2009, 16:22, archived)
# are
tangerines in season just now?
(I helped save b3ta! Prof UnderCover evitable, Fri 27 Mar 2009, 16:26, archived)
# use a pomegranate
(I helped save b3ta! Griffin Saver Something, something, 2006, something., Fri 27 Mar 2009, 16:28, archived)
# good call
clever old stick
(I helped save b3ta! Prof UnderCover evitable, Fri 27 Mar 2009, 16:28, archived)
# MDMA is amazing
... or ... stay straight all weekend. Lazy Sunday morning where you can read the papers... Give Mrs Vagabond a 6 minute head start and then chase her...
(I helped save b3ta! Prof UnderCover evitable, Fri 27 Mar 2009, 16:26, archived)
# buy a cravat
and wear it
(I helped save b3ta! Prof UnderCover evitable, Fri 27 Mar 2009, 16:29, archived)
# ...
catch the train somewhere lovely and go there...
(I helped save b3ta! Prof UnderCover evitable, Fri 27 Mar 2009, 16:31, archived)
# Get you...
Full of jaunty weekend ideas :D
(I helped save b3ta! The magic of chutney Shakes it like an Instagram filter!, Fri 27 Mar 2009, 16:31, archived)
# I know
I'm finding it very hard to think of things that don't end up sitting in a Samuel Smith's bar pub putting the world to rights...

or naked on a tandem

I'd be very disappointed with myself if they weren't awesome ideas and I wasn't already drunk
(I helped save b3ta! Prof UnderCover evitable, Fri 27 Mar 2009, 16:33, archived)
# ha ha
super stuff
(I helped save b3ta! The magic of chutney Shakes it like an Instagram filter!, Fri 27 Mar 2009, 16:39, archived)
# LEGO LAND!
... chessington world of disappointment...

see some of your friends who have children...
(I helped save b3ta! Prof UnderCover evitable, Fri 27 Mar 2009, 16:35, archived)
# I have quite enjoyed lego land
but I was drunk.
(_Felix 's school of dance and occult sciences, Fri 27 Mar 2009, 17:01, archived)
# buy a pipe and some rough shag
stick one in the other and smoke!

Read Fear and Loathing in Las Vegas...

download and listen to as much Just a Minute as you can do...

try and stalk Melvyn Bragg...
(I helped save b3ta! Prof UnderCover evitable, Fri 27 Mar 2009, 16:37, archived)
# make a pin hole camera!
(I helped save b3ta! Prof UnderCover evitable, Fri 27 Mar 2009, 16:37, archived)
# .....!!! Now steady on
Are you reading my "to do" list? *awaits delivery of developing fluid*
(I helped save b3ta! The magic of chutney Shakes it like an Instagram filter!, Fri 27 Mar 2009, 16:42, archived)
# :D
(I helped save b3ta! Prof UnderCover evitable, Fri 27 Mar 2009, 16:43, archived)
# make a camera obscura in your living room!
then photograph the results
(I helped save b3ta! Prof UnderCover evitable, Fri 27 Mar 2009, 16:40, archived)
# some sort of DVD marathon
(I helped save b3ta! Prof UnderCover evitable, Fri 27 Mar 2009, 16:41, archived)
# sell things on eBay
... make things to sell on eBay
(I helped save b3ta! Prof UnderCover evitable, Fri 27 Mar 2009, 16:43, archived)
# exit your house thorugh your front door
walk some distance and then STOP... turn slowly 360 degrees on the spot and find the tallest thing you can see on the horizon - go to it and climb it (this is how I ended up at the top of North Berwick Law!)
(I helped save b3ta! Prof UnderCover evitable, Fri 27 Mar 2009, 16:49, archived)