'Significant' is more acceptable that 'life changing'. As BGB alluded to, YOU change your life and the music acts as an instigator/soundtrack
Aphex Twin - Digiridoo, electronic music from the future. Made all the insipid rave stuff sound foolish and flaccid.

Faust - Tapes, electronic music from the past. Incredible cut up journey that oscillates between aural angels of mercy and angels of death. Opened the doors of Krautrock.

Captain Beefheart - Moonlight on Vermont, gravelly preacher man psychedelic blues. No one sounds like the Captain.

Crooked Jades - Sandy Boys, heard this by pure chance on Radio 2. Stunning track by a truly unbelievable band. Changed everything I believed about live music.

Nick Drake - Cello Song, left me stunned and dazed. Beautifully timeless
(Cancer Joy was short lived, Wed 7 Sep 2011, 20:02, 2 replies, latest was 15 years ago)

I'm not sure if that's true
Sometimes you vacciliate, and a musical message resonates and pushes you on.
( The Disappointed Caravanner of the year, Wed 7 Sep 2011, 20:19, Reply)

Didgeridoo is tremendous.
Come to Daddy was equally seminal. Windowlicker even more so. Windowlicker still sounds like some future science shit, but it's over ten years old now.
(dozers, do fuck off ur a nob m8, Wed 7 Sep 2011, 20:24, Reply)

I love Windowlicker.

( girlinthehole, Wed 7 Sep 2011, 20:25, Reply)

You are a windowlicker.

( b3th Not shit. Not mod., Wed 7 Sep 2011, 20:29, Reply)

It's an incredible piece of music.

(dozers, do fuck off ur a nob m8, Wed 7 Sep 2011, 20:30, Reply)

The video blew me away too.

( girlinthehole, Wed 7 Sep 2011, 20:31, Reply)

Have you seen the one for Come to Daddy?

(dozers, do fuck off ur a nob m8, Wed 7 Sep 2011, 20:34, Reply)

No, I will youtube now.
Edit - Ah yes I have. I fucking love their videos : )
( girlinthehole, Wed 7 Sep 2011, 20:35, Reply)

Chris Cunningham is great.
He also did this one for Bjork

www.youtube.com/watch?v=wxBO28j3vug
(dozers, do fuck off ur a nob m8, Wed 7 Sep 2011, 20:42, Reply)

I like that.
Great song too. I've never heard that song before.
( girlinthehole, Wed 7 Sep 2011, 20:46, Reply)

It's a beautiful video.
JAPANESE ROBOT LESBIANS KISSING!

For the lower of brow among us.
(dozers, do fuck off ur a nob m8, Wed 7 Sep 2011, 20:51, Reply)

ALWAYS A WINNA!!!

( girlinthehole, Wed 7 Sep 2011, 20:52, Reply)

For more Japanese schoolgirl Chris Cunningham goodness...
LFO's Freak and Squarepusher's Come on my Selector.
(dozers, do fuck off ur a nob m8, Wed 7 Sep 2011, 20:54, Reply)

that's made me watch it
*touches chin with brow*
( The Light in Chains don't touch the Pope's boner, Wed 7 Sep 2011, 21:00, Reply)

Did you like it?
Dancing Japanese schoolgirls in the Freak video.
(dozers, do fuck off ur a nob m8, Wed 7 Sep 2011, 21:09, Reply)

very bjorky

( The Light in Chains don't touch the Pope's boner, Wed 7 Sep 2011, 22:30, Reply)